SHENZHEN TIDE BIOTECH LTD

The main protraction mechanism of semaglutide is albumin binding, facilitated by modification of position 26 lysine with a hydrophilic spacer and a C18 fatty di-acid. Furthermore, semaglutide is modified in position 8 to provide stabilization against degradation by the enzyme dipeptidyl-peptidase 4 (DPP-4). A minor modification was made in position 34 to ensure the attachment of only one fatty di-acid. The molecular formula is C187H291N45O59 and the molecular weight is 4113.58 g/mol.

water content:5.95%

Purity:99.4%

High polymer protein:0.029%

pH:7.9

Peptide Content:91.2%

Microbial Limits：N.D

Bacterial Endotoxins：Conforms

Host Cell Protein：Conforms

Host Cell DNA：Conforms

Total impurities：0.56%